19F multiple-quantum coherence NMR spectroscopy for probing protein–ligand interactions

2′-SCF3 Uridine–A Powerful Label for Probing Structure and Function of RNA by 19F NMR Spectroscopy**

Fluorishing: the Togni reagent allows efficient synthetic access to fluorine-labeled RNA molecules. These are in turn highly useful for NMR spectroscopic analyses of secondary and tertiary structures, RNA-protein interactions, and functionality of riboswitch modules.

Galactose oxidase models: insights from 19F NMR spectroscopy.

(19)F labelled tripodal ligands that possess a N(3)O donor set (one phenol, one tertiary amine and either two pyridines or one pyridine and one quinoline) have been synthesized. The fluorine is incorporated either at the phenol O-donor (HL(F) and HL(CF3)) or at the quinoline N-donor (HLq(OMe) and HLq(NO2)). The copper(ii)-phenol complexes (2H)(2+), (1H)(2+), (3H)(2+) and (4H)(2+) as well as the...

Ultrafast double-quantum NMR spectroscopy.

We demonstrate the acquisition of double-quantum NMR spectra in less than three seconds and illustrate the synergies between double-quantum and ultrafast NMR spectroscopy for the analysis of complex mixtures.

Double-Quantum MAS NMR Spectroscopy

Multiple - Quantum Magic - Angle Spinning NMR: A New Technique for Probing Quadrupolar Nuclei in Solids

Recentemente descrevemos um nova técnica capaz de obter espectros de RMN de alta resolução de núcleos quadrupolares com spins múltiplos de 1/2 no estado sólido, baseada no uso combinado de rotação no ângulo mágico (MAS) e espectroscopia múltipla quântica (MQ). Esta revisão descreve aspectos da teoria básica que suporta o experimento de RMN MQMAS de alta resolução e também enfatiza aspectos prát...